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change in a single base (nucleotide) on Tdpb gene, which encodes the protein Tdp-43. From previous research we know that this protein accumulates in t

there is no treatment. Shaw and colleagues studied the first time in a hereditary form of the disease, which affects 5 percent of patients. Screening of 154 people showed that 4 components of a

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in the familial form of the disease that is sporadic, affecting "coincidence" without inheritance, 95 per cent of the sick. In a later researchers have sequenced the same gene in 372 patients Tdpb the sporadic f