Italian researcher Alessandra Luchini wins the first edition of "The Prize Award” with a paper of a system to identify those molecules that signal the presence of a tumor (tumor markers) that are beyond the traditional methods of investigation. To do this requires making a hydrogel containing certain microscopic nano-spheres that once inserted in the samples of blood taken for analysis diagnostic trap some markers and protect them from deterioration. "These nano-spheres, made of the same plastic as hydrated soft contact lenses are equipped with special molecules that, once in the blood, snap-specific tumor markers and incorporate them. In this way, they protect them from enzymes that would otherwise deteriorate them. Usually blood tests fail to identify precisely because these markers are destroyed prematurely, " says researcher Alessandra Luchini. "The beauty of this system," says the researcher, "is that it does not need very sophisticated tools, which is simple and economical: with one hundred U.S. dollars we can make nano-spheres for more than two hundred patients." The new method is not going to replace the standard, but acts at a stage prior to analysis by providing a better quality.

Muliple mutations of a single gene lead to the accumulation of a protein in motor neurons that causes death. Mutations in a single gene could be the basis of amyotrophic lateral sclerosis (Sla), the neurodegenerative disease that leads to progressive paralysis and that affects every year in Italy 1,500 people, mainly men of average or advanced age. The discovery, the result of years of studies conducted by international team in which the names of Emanuele Buratti Baralle Francisco and the International Centre for Genetic Engineering and Biotechnology (Icgeb) in Trieste, and guided by Christopher Shaw of King College London, appeared in Science.