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Search Result for: pile Ouch
If stupidity would hurt, then these guys would be yelling in pain. Oh, wait a minute...they are yelling in pain. Those morons decided to jump from the top of the roof, one on top of the other. It's called a piledriver (or is it pile driver?)
Amazing
After a raid on a drug dealer in Mexico, the cops were stunned to find 207 million dollars in cash piled in one of the house's bedrooms. Wow! Now that's an amazing find!
Technology and Health News
Npas4: This protein regulates the formation of inhibitory synapses between neurons.
The inhibitory activity of neurons is regulated by a particular switch. This is a protein involved in the formation and maintenance of synapses in regulating selectively switching the electrical signal between nerve cells. Its name is Npas4 and was discovered by researchers from the Children's Hospital in Boston this week to publish their study in Nature.
In particular, the protein in question is a transcription factor, that is a molecule that can activate or deactivate specific genes. Those which would be linked to Npas4 are more than 270. When the protein is produced in large quantities, we are seeing an increase in the number of inhibitory synapses on the surface of nerve cells.
But what induces the production of high levels of Npas4? According to the researchers this is a reaction to excitatory synaptic. "It is as if the same excitement triggers a program to rebalance the brain with inhibition," says Michael Greenberg, coordinator of the study, which continues: "The mice in which the protein is suppressed, in fact, have neurological problems: are anxious, hyperactive and more subject to seizures. " The discovery could help researchers in studying these disorders. Inhibition, in fact, plays an important role in brain development.
An experimental study opens a way for gene therapy as a possible treatment for cases that do not respond to medicines in cases of Epilepsy. Research on Brain.
Almost one third of people suffering from epilepsy don't respond to prescription drugs. To date, the only possibility for many of them is to undergo an operation to remove the area affected by the disease in the brain, but an alternative to surgery could rise by gene therapy.
An experimental study of the Department of Neuroscience of Mario Negri in Milan, led by Noah, has shown that it is possible to induce the sick cells to produce a protein with anticonvulsant properties. And what this substance does is significantly reduces the recurrence of seizures.
The research, conducted in collaboration with international groups led by Gunther Sperk University of Innsbruck (Austria), Asla Pitkanen University of Kuopio (Finland), and Matthew During dell'Ohio State University (USA), was just published on Brain magazine.
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